Cell-free DNA TAPS provides multimodal information for early cancer detection

Multimodal, genome-wide characterization of epigenetic and genetic information in circulating cell-free DNA (cfDNA) could enable more sensitive early cancer detection, but it is technologically challenging. Recently, we developed TET-assisted pyridine borane sequencing (TAPS), which is a mild, bisul...

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Detalles Bibliográficos
Autores principales: Siejka-Zielińska, Paulina, Cheng, Jingfei, Jackson, Felix, Liu, Yibin, Soonawalla, Zahir, Reddy, Srikanth, Silva, Michael, Puta, Luminita, McCain, Misti Vanette, Culver, Emma L., Bekkali, Noor, Schuster-Böckler, Benjamin, Palamara, Pier Francesco, Mann, Derek, Reeves, Helen, Barnes, Eleanor, Sivakumar, Shivan, Song, Chun-Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442905/
https://www.ncbi.nlm.nih.gov/pubmed/34516908
http://dx.doi.org/10.1126/sciadv.abh0534

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