Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques

There is an urgent requirement for safe and effective vaccines to prevent COVID-19. A concern for the development of new viral vaccines is the potential to induce vaccine-enhanced disease (VED). This was reported in several preclinical studies with both SARS-CoV-1 and MERS vaccines but has not been...

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Detalles Bibliográficos
Autores principales: Bewley, Kevin R., Gooch, Karen, Thomas, Kelly M., Longet, Stephanie, Wiblin, Nathan, Hunter, Laura, Chan, Kin, Brown, Phillip, Russell, Rebecca A., Ho, Catherine, Slack, Gillian, Humphries, Holly E., Alden, Leonie, Allen, Lauren, Aram, Marilyn, Baker, Natalie, Brunt, Emily, Cobb, Rebecca, Fotheringham, Susan, Harris, Debbie, Kennard, Chelsea, Leung, Stephanie, Ryan, Kathryn, Tolley, Howard, Wand, Nadina, White, Andrew, Sibley, Laura, Sarfas, Charlotte, Pearson, Geoff, Rayner, Emma, Xue, Xiaochao, Lambe, Teresa, Charlton, Sue, Gilbert, Sarah, Sattentau, Quentin J., Gleeson, Fergus, Hall, Yper, Funnell, Simon, Sharpe, Sally, Salguero, Francisco J., Gorringe, Andrew, Carroll, Miles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442907/
https://www.ncbi.nlm.nih.gov/pubmed/34516768
http://dx.doi.org/10.1126/sciadv.abg7996

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