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dic(7;9)(p11–13;p11)

Dicentric (7;9)(p11–13;p11) is a rare but recurrent abnormality in pediatric and adult precursor B acute lymphoblastic leukemia (B-ALL). The rarity precludes a deep understanding of its biology and associated prognosis. However, recent findings have correlated dic(7;9) and PAX5 mutations, highlighti...

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Detalles Bibliográficos
Autores principales: Underdown, Mary J, Russell, Thomas B, Pettenati, Mark J, Kram, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442920/
https://www.ncbi.nlm.nih.gov/pubmed/34531928
http://dx.doi.org/10.4267/2042/38299
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author Underdown, Mary J
Russell, Thomas B
Pettenati, Mark J
Kram, David E
author_facet Underdown, Mary J
Russell, Thomas B
Pettenati, Mark J
Kram, David E
author_sort Underdown, Mary J
collection PubMed
description Dicentric (7;9)(p11–13;p11) is a rare but recurrent abnormality in pediatric and adult precursor B acute lymphoblastic leukemia (B-ALL). The rarity precludes a deep understanding of its biology and associated prognosis. However, recent findings have correlated dic(7;9) and PAX5 mutations, highlighting this cytogenetic event’s involvement in leukemogenesis and may also shed light on the overall prognosis of dic(7;9) B-ALL.
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spelling pubmed-84429202021-09-15 dic(7;9)(p11–13;p11) Underdown, Mary J Russell, Thomas B Pettenati, Mark J Kram, David E Atlas Genet Cytogenet Oncol Haematol Article Dicentric (7;9)(p11–13;p11) is a rare but recurrent abnormality in pediatric and adult precursor B acute lymphoblastic leukemia (B-ALL). The rarity precludes a deep understanding of its biology and associated prognosis. However, recent findings have correlated dic(7;9) and PAX5 mutations, highlighting this cytogenetic event’s involvement in leukemogenesis and may also shed light on the overall prognosis of dic(7;9) B-ALL. 2006 /pmc/articles/PMC8442920/ /pubmed/34531928 http://dx.doi.org/10.4267/2042/38299 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence.
spellingShingle Article
Underdown, Mary J
Russell, Thomas B
Pettenati, Mark J
Kram, David E
dic(7;9)(p11–13;p11)
title dic(7;9)(p11–13;p11)
title_full dic(7;9)(p11–13;p11)
title_fullStr dic(7;9)(p11–13;p11)
title_full_unstemmed dic(7;9)(p11–13;p11)
title_short dic(7;9)(p11–13;p11)
title_sort dic(7;9)(p11–13;p11)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442920/
https://www.ncbi.nlm.nih.gov/pubmed/34531928
http://dx.doi.org/10.4267/2042/38299
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