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dic(7;9)(p11–13;p11)
Dicentric (7;9)(p11–13;p11) is a rare but recurrent abnormality in pediatric and adult precursor B acute lymphoblastic leukemia (B-ALL). The rarity precludes a deep understanding of its biology and associated prognosis. However, recent findings have correlated dic(7;9) and PAX5 mutations, highlighti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442920/ https://www.ncbi.nlm.nih.gov/pubmed/34531928 http://dx.doi.org/10.4267/2042/38299 |
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author | Underdown, Mary J Russell, Thomas B Pettenati, Mark J Kram, David E |
author_facet | Underdown, Mary J Russell, Thomas B Pettenati, Mark J Kram, David E |
author_sort | Underdown, Mary J |
collection | PubMed |
description | Dicentric (7;9)(p11–13;p11) is a rare but recurrent abnormality in pediatric and adult precursor B acute lymphoblastic leukemia (B-ALL). The rarity precludes a deep understanding of its biology and associated prognosis. However, recent findings have correlated dic(7;9) and PAX5 mutations, highlighting this cytogenetic event’s involvement in leukemogenesis and may also shed light on the overall prognosis of dic(7;9) B-ALL. |
format | Online Article Text |
id | pubmed-8442920 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
record_format | MEDLINE/PubMed |
spelling | pubmed-84429202021-09-15 dic(7;9)(p11–13;p11) Underdown, Mary J Russell, Thomas B Pettenati, Mark J Kram, David E Atlas Genet Cytogenet Oncol Haematol Article Dicentric (7;9)(p11–13;p11) is a rare but recurrent abnormality in pediatric and adult precursor B acute lymphoblastic leukemia (B-ALL). The rarity precludes a deep understanding of its biology and associated prognosis. However, recent findings have correlated dic(7;9) and PAX5 mutations, highlighting this cytogenetic event’s involvement in leukemogenesis and may also shed light on the overall prognosis of dic(7;9) B-ALL. 2006 /pmc/articles/PMC8442920/ /pubmed/34531928 http://dx.doi.org/10.4267/2042/38299 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence. |
spellingShingle | Article Underdown, Mary J Russell, Thomas B Pettenati, Mark J Kram, David E dic(7;9)(p11–13;p11) |
title | dic(7;9)(p11–13;p11) |
title_full | dic(7;9)(p11–13;p11) |
title_fullStr | dic(7;9)(p11–13;p11) |
title_full_unstemmed | dic(7;9)(p11–13;p11) |
title_short | dic(7;9)(p11–13;p11) |
title_sort | dic(7;9)(p11–13;p11) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442920/ https://www.ncbi.nlm.nih.gov/pubmed/34531928 http://dx.doi.org/10.4267/2042/38299 |
work_keys_str_mv | AT underdownmaryj dic79p1113p11 AT russellthomasb dic79p1113p11 AT pettenatimarkj dic79p1113p11 AT kramdavide dic79p1113p11 |