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Amyloid beta emerges from below the neck to disable the brain

Accumulation of amyloid beta (Aβ) in the brain in Alzheimer disease drives pathophysiology. A study in this issue of PLOS Biology revealed that Aβ from the liver can promote brain pathology, supporting that peripheral Aβ can contribute to neurodegeneration.

Detalles Bibliográficos
Autores principales: Kauwe, Grant, Tracy, Tara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443044/
https://www.ncbi.nlm.nih.gov/pubmed/34525093
http://dx.doi.org/10.1371/journal.pbio.3001388
Descripción
Sumario:Accumulation of amyloid beta (Aβ) in the brain in Alzheimer disease drives pathophysiology. A study in this issue of PLOS Biology revealed that Aβ from the liver can promote brain pathology, supporting that peripheral Aβ can contribute to neurodegeneration.