Amyloid beta emerges from below the neck to disable the brain

Accumulation of amyloid beta (Aβ) in the brain in Alzheimer disease drives pathophysiology. A study in this issue of PLOS Biology revealed that Aβ from the liver can promote brain pathology, supporting that peripheral Aβ can contribute to neurodegeneration.

Detalles Bibliográficos
Autores principales: Kauwe, Grant, Tracy, Tara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443044/
https://www.ncbi.nlm.nih.gov/pubmed/34525093
http://dx.doi.org/10.1371/journal.pbio.3001388
_version_ 1783753111816372224
author Kauwe, Grant
Tracy, Tara E.
author_facet Kauwe, Grant
Tracy, Tara E.
author_sort Kauwe, Grant
collection PubMed
description Accumulation of amyloid beta (Aβ) in the brain in Alzheimer disease drives pathophysiology. A study in this issue of PLOS Biology revealed that Aβ from the liver can promote brain pathology, supporting that peripheral Aβ can contribute to neurodegeneration.
format Online
Article
Text
id pubmed-8443044
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-84430442021-09-16 Amyloid beta emerges from below the neck to disable the brain Kauwe, Grant Tracy, Tara E. PLoS Biol Primer Accumulation of amyloid beta (Aβ) in the brain in Alzheimer disease drives pathophysiology. A study in this issue of PLOS Biology revealed that Aβ from the liver can promote brain pathology, supporting that peripheral Aβ can contribute to neurodegeneration. Public Library of Science 2021-09-15 /pmc/articles/PMC8443044/ /pubmed/34525093 http://dx.doi.org/10.1371/journal.pbio.3001388 Text en © 2021 Kauwe, Tracy https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Primer
Kauwe, Grant
Tracy, Tara E.
Amyloid beta emerges from below the neck to disable the brain
title Amyloid beta emerges from below the neck to disable the brain
title_full Amyloid beta emerges from below the neck to disable the brain
title_fullStr Amyloid beta emerges from below the neck to disable the brain
title_full_unstemmed Amyloid beta emerges from below the neck to disable the brain
title_short Amyloid beta emerges from below the neck to disable the brain
title_sort amyloid beta emerges from below the neck to disable the brain
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443044/
https://www.ncbi.nlm.nih.gov/pubmed/34525093
http://dx.doi.org/10.1371/journal.pbio.3001388
work_keys_str_mv AT kauwegrant amyloidbetaemergesfrombelowthenecktodisablethebrain
AT tracytarae amyloidbetaemergesfrombelowthenecktodisablethebrain

Ejemplares similares