Renal Microvascular Ischemia Secondary to Nonsteroidal Anti-inflammatory Drugs

Nonsteroidal anti-inflammatory drugs (NSAIDs), widely prescribed for pain, can affect kidneys in various ways. We present a case of a 37-year-old woman with multiple NSAIDs intake over a short period for dysmenorrhea followed by the development of new-onset bilateral flank pain. Computed tomography...

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Detalles Bibliográficos
Autores principales: Kulkarni, Sagar, Chakurkar, Vipul, Lobo, Valentine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443091/
https://www.ncbi.nlm.nih.gov/pubmed/34584355
http://dx.doi.org/10.4103/ijn.IJN_211_20
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author Kulkarni, Sagar
Chakurkar, Vipul
Lobo, Valentine
author_facet Kulkarni, Sagar
Chakurkar, Vipul
Lobo, Valentine
author_sort Kulkarni, Sagar
collection PubMed
description Nonsteroidal anti-inflammatory drugs (NSAIDs), widely prescribed for pain, can affect kidneys in various ways. We present a case of a 37-year-old woman with multiple NSAIDs intake over a short period for dysmenorrhea followed by the development of new-onset bilateral flank pain. Computed tomography revealed bilateral multiple renal infarcts. Renal function was normal. Investigations showed no cardiac or renal artery lesion and vasculitis work-up was negative. She was treated conservatively and further NSAID intake was avoided. Follow-up scan showed complete restoration of the blood flow in previously affected areas. Thus, microvascular ischemia secondary to NSAIDs was thought to be responsible.
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spelling pubmed-84430912021-09-27 Renal Microvascular Ischemia Secondary to Nonsteroidal Anti-inflammatory Drugs Kulkarni, Sagar Chakurkar, Vipul Lobo, Valentine Indian J Nephrol Case Report Nonsteroidal anti-inflammatory drugs (NSAIDs), widely prescribed for pain, can affect kidneys in various ways. We present a case of a 37-year-old woman with multiple NSAIDs intake over a short period for dysmenorrhea followed by the development of new-onset bilateral flank pain. Computed tomography revealed bilateral multiple renal infarcts. Renal function was normal. Investigations showed no cardiac or renal artery lesion and vasculitis work-up was negative. She was treated conservatively and further NSAID intake was avoided. Follow-up scan showed complete restoration of the blood flow in previously affected areas. Thus, microvascular ischemia secondary to NSAIDs was thought to be responsible. Wolters Kluwer - Medknow 2021 2020-11-07 /pmc/articles/PMC8443091/ /pubmed/34584355 http://dx.doi.org/10.4103/ijn.IJN_211_20 Text en Copyright: © 2020 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kulkarni, Sagar
Chakurkar, Vipul
Lobo, Valentine
Renal Microvascular Ischemia Secondary to Nonsteroidal Anti-inflammatory Drugs
title Renal Microvascular Ischemia Secondary to Nonsteroidal Anti-inflammatory Drugs
title_full Renal Microvascular Ischemia Secondary to Nonsteroidal Anti-inflammatory Drugs
title_fullStr Renal Microvascular Ischemia Secondary to Nonsteroidal Anti-inflammatory Drugs
title_full_unstemmed Renal Microvascular Ischemia Secondary to Nonsteroidal Anti-inflammatory Drugs
title_short Renal Microvascular Ischemia Secondary to Nonsteroidal Anti-inflammatory Drugs
title_sort renal microvascular ischemia secondary to nonsteroidal anti-inflammatory drugs
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443091/
https://www.ncbi.nlm.nih.gov/pubmed/34584355
http://dx.doi.org/10.4103/ijn.IJN_211_20
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AT chakurkarvipul renalmicrovascularischemiasecondarytononsteroidalantiinflammatorydrugs
AT lobovalentine renalmicrovascularischemiasecondarytononsteroidalantiinflammatorydrugs

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