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Rapidly growing sclerosing angiomatoid nodular transformation of the spleen
Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign vascular lesion with unknown pathogenesis and no definitive pathognomonic radiological features. The majority of patients with SANT are asymptomatic, and the lesion is an incidental finding on cross-sectional imaging...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443271/ https://www.ncbi.nlm.nih.gov/pubmed/34540195 http://dx.doi.org/10.1093/jscr/rjab323 |
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author | Sohail, Amir Humza Eze, Anthony Sohail, Sachal Hadi, Yousaf Bashir Haider, Zishan Maurer, James |
author_facet | Sohail, Amir Humza Eze, Anthony Sohail, Sachal Hadi, Yousaf Bashir Haider, Zishan Maurer, James |
author_sort | Sohail, Amir Humza |
collection | PubMed |
description | Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign vascular lesion with unknown pathogenesis and no definitive pathognomonic radiological features. The majority of patients with SANT are asymptomatic, and the lesion is an incidental finding on cross-sectional imaging performed for unrelated reasons or during intra-abdominal surgery. However, in the symptomatic minority, abdominal pain is the most commonly reported symptom. SANT generally remains stable or has very slow growth, making it amenable to surveillance using serial cross-sectional imaging. Herein, we report the unusual case of SANT in a 30-year-old female with rapid growth from 6.0 × 5.6 × 4.4 cm to 8.0 × 6.6 × 7.2 cm over 21 months. Given the rapid growth, it was imperative to rule out malignancy. Thus, the patient underwent a laparoscopic total splenectomy. For SANT, splenectomy serves the dual purpose of diagnosis and definitive therapy. |
format | Online Article Text |
id | pubmed-8443271 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-84432712021-09-16 Rapidly growing sclerosing angiomatoid nodular transformation of the spleen Sohail, Amir Humza Eze, Anthony Sohail, Sachal Hadi, Yousaf Bashir Haider, Zishan Maurer, James J Surg Case Rep Case Report Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign vascular lesion with unknown pathogenesis and no definitive pathognomonic radiological features. The majority of patients with SANT are asymptomatic, and the lesion is an incidental finding on cross-sectional imaging performed for unrelated reasons or during intra-abdominal surgery. However, in the symptomatic minority, abdominal pain is the most commonly reported symptom. SANT generally remains stable or has very slow growth, making it amenable to surveillance using serial cross-sectional imaging. Herein, we report the unusual case of SANT in a 30-year-old female with rapid growth from 6.0 × 5.6 × 4.4 cm to 8.0 × 6.6 × 7.2 cm over 21 months. Given the rapid growth, it was imperative to rule out malignancy. Thus, the patient underwent a laparoscopic total splenectomy. For SANT, splenectomy serves the dual purpose of diagnosis and definitive therapy. Oxford University Press 2021-09-15 /pmc/articles/PMC8443271/ /pubmed/34540195 http://dx.doi.org/10.1093/jscr/rjab323 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2021. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Sohail, Amir Humza Eze, Anthony Sohail, Sachal Hadi, Yousaf Bashir Haider, Zishan Maurer, James Rapidly growing sclerosing angiomatoid nodular transformation of the spleen |
title | Rapidly growing sclerosing angiomatoid nodular transformation of the spleen |
title_full | Rapidly growing sclerosing angiomatoid nodular transformation of the spleen |
title_fullStr | Rapidly growing sclerosing angiomatoid nodular transformation of the spleen |
title_full_unstemmed | Rapidly growing sclerosing angiomatoid nodular transformation of the spleen |
title_short | Rapidly growing sclerosing angiomatoid nodular transformation of the spleen |
title_sort | rapidly growing sclerosing angiomatoid nodular transformation of the spleen |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443271/ https://www.ncbi.nlm.nih.gov/pubmed/34540195 http://dx.doi.org/10.1093/jscr/rjab323 |
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