Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity

Fibroblasts display extensive transcriptional heterogeneity, yet functional annotation and characterization of their heterocellular relationships remains incomplete. Using mass cytometry, we chart the stromal composition of 18 murine tissues and 5 spontaneous tumor models, with an emphasis on mesenc...

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Detalles Bibliográficos
Autores principales: Hutton, Colin, Heider, Felix, Blanco-Gomez, Adrian, Banyard, Antonia, Kononov, Alexander, Zhang, Xiaohong, Karim, Saadia, Paulus-Hock, Viola, Watt, Dale, Steele, Nina, Kemp, Samantha, Hogg, Elizabeth K.J., Kelly, Joanna, Jackstadt, Rene-Filip, Lopes, Filipa, Menotti, Matteo, Chisholm, Luke, Lamarca, Angela, Valle, Juan, Sansom, Owen J., Springer, Caroline, Malliri, Angeliki, Marais, Richard, Pasca di Magliano, Marina, Zelenay, Santiago, Morton, Jennifer P., Jørgensen, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443274/
https://www.ncbi.nlm.nih.gov/pubmed/34297917
http://dx.doi.org/10.1016/j.ccell.2021.06.017

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