Cargando…

GDF-15 Suppresses Atherosclerosis by Inhibiting oxLDL-Induced Lipid Accumulation and Inflammation in Macrophages

The growth differentiation factor-15 (GDF-15) may be involved in atherosclerosis. However, the role of GDF-15 in atherosclerosis remains unclear. The main goal of this study was to verify the role and mechanism of GDF-15 in atherogenesis. We first compared the serum GDF-15 level between patients wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Hong, Chen, Zhongli, Li, Yan, Gong, Kunmei, Xiao, Le, Fu, Hao, Yang, Jingjing, Wang, Xianying, Meng, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443352/ https://www.ncbi.nlm.nih.gov/pubmed/34539804 http://dx.doi.org/10.1155/2021/6497568

Ejemplares similares

LOX-1, OxLDL, and Atherosclerosis
por: Pirillo, Angela, et al.
Publicado: (2013)

Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL
por: Kimmel, Danielle W., et al.
Publicado: (2017)

oxLDL and eLDL Induced Membrane Microdomains in Human Macrophages
por: Wallner, Stefan, et al.
Publicado: (2016)

β Common Receptor Mediates Erythropoietin-Conferred Protection on OxLDL-Induced Lipid Accumulation and Inflammation in Macrophages
por: Lee, Tzong-Shyuan, et al.
Publicado: (2015)

Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation
por: Houben, Tom, et al.
Publicado: (2017)

Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2021)

Data on autophagy markers in human macrophages exposed to oxLDL and growth differentiation factor-15
por: Ackermann, Kathrin, et al.
Publicado: (2019)

LXRα Regulates oxLDL-Induced Trained Immunity in Macrophages
por: Findeisen, Hannes M., et al.
Publicado: (2022)

The association between serum levels of oxLDL-lgG and oxLDL-lgM autoantibody with adult acute myeloblastic leukaemia
por: Li, Hao, et al.
Publicado: (2010)

Impact of oxLDL on Cholesterol-Rich Membrane Rafts
por: Levitan, Irena, et al.
Publicado: (2011)

Niacin Reverses Migratory Macrophage Foam Cell Arrest Mediated by oxLDL In Vitro
por: Huang, Hua, et al.
Publicado: (2014)

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy
por: Gutwein, Paul, et al.
Publicado: (2009)

OxLDL as an Inducer of a Metabolic Shift in Cancer Cells
por: Bitorina, Albert V., et al.
Publicado: (2021)

Activation of TRPV1 Prevents OxLDL-Induced Lipid Accumulation and TNF-α-Induced Inflammation in Macrophages: Role of Liver X Receptor α
por: Zhao, Jin-Feng, et al.
Publicado: (2013)

Activation of GPR55 Receptors Exacerbates oxLDL-Induced Lipid Accumulation and Inflammatory Responses, while Reducing Cholesterol Efflux from Human Macrophages
por: Lanuti, Mirko, et al.
Publicado: (2015)

Uptake of oxLDL and IL-10 Production by Macrophages Requires PAFR and CD36 Recruitment into the Same Lipid Rafts
por: Rios, Francisco J. O., et al.
Publicado: (2013)

Early Transcriptomic Response to LDL and oxLDL in Human Vascular Smooth Muscle Cells
por: Damián-Zamacona, Salvador, et al.
Publicado: (2016)

Co-Stimulation of PAFR and CD36 Is Required for oxLDL-Induced Human Macrophages Activation
por: Rios, Francisco J. O., et al.
Publicado: (2012)

Dyslipidemia-Induced Neuropathy in Mice: The Role of oxLDL/LOX-1
por: Vincent, Andrea M., et al.
Publicado: (2009)

oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming
por: Groh, Laszlo A., et al.
Publicado: (2021)

Correction: Activation of GPR55 Receptors Exacerbates oxLDL-Induced Lipid Accumulation and Inflammatory Responses, while Reducing Cholesterol Efflux from Human Macrophages
por: Lanuti, Mirko, et al.
Publicado: (2015)

Puerarin Inhibits oxLDL-Induced Macrophage Activation and Foam Cell Formation in Human THP1 Macrophage
por: Zhang, Heng, et al.
Publicado: (2015)

Piceatannol inhibits pyroptosis and suppresses oxLDL-induced lipid storage in macrophages by regulating miR-200a/Nrf2/GSDMD axis
por: Mu, Zhongyuan, et al.
Publicado: (2020)

M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes
por: Isa, Suleiman A, et al.
Publicado: (2011)

Retraction: Piceatannol inhibits pyroptosis and suppresses oxLDL-induced lipid storage in macrophages by regulating miR-200a/Nrf2/GSDMD axis
Publicado: (2021)

Systems Approach to Study Associations between OxLDL and Abdominal Aortic Aneurysms
por: Gutowski, Łukasz, et al.
Publicado: (2019)

Early Transcriptomic Response to OxLDL in Human Retinal Pigment Epithelial Cells
por: Koirala, Diwa, et al.
Publicado: (2020)

Astragaloside IV Reduces OxLDL-Induced BNP Overexpression by Regulating HDAC
por: Zhang, Wenting, et al.
Publicado: (2021)

Immune modulatory effects of progesterone on oxLDL‐induced trained immunity in monocytes
por: Groh, Laszlo A., et al.
Publicado: (2022)

Exposure to oxLDL impairs TGF-β activity in human tendon cells
por: Mousavizadeh, Rouhollah, et al.
Publicado: (2023)

Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages
por: Varì, Rosaria, et al.
Publicado: (2015)

Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction
por: Vrieling, Frank, et al.
Publicado: (2019)

GDF-15 protects from macrophage accumulation in a mousemodel of advanced atherosclerosis
por: Preusch, Michael R, et al.
Publicado: (2013)

Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice
por: van der Vorst, Emiel P. C., et al.
Publicado: (2023)

Passive Immunization with Hypochlorite-oxLDL Specific Antibodies Reduces Plaque Volume in LDL Receptor-Deficient Mice
por: van Leeuwen, Marcella, et al.
Publicado: (2013)

Ethyl pyruvate inhibits oxidation of LDL in vitro and attenuates oxLDL toxicity in EA.hy926 cells
por: Rossmann, Christine, et al.
Publicado: (2018)

oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21
por: Nickel, Thomas, et al.
Publicado: (2012)

Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice
por: Talbot, Maude, et al.
Publicado: (2018)

Bone marrow-derived and peritoneal macrophages have different inflammatory response to oxLDL and M1/M2 marker expression – implications for atherosclerosis research
por: Bisgaard, Line S., et al.
Publicado: (2016)

oxLDL antibody inhibits MCP‐1 release in monocytes/macrophages by regulating Ca(2+)/K(+) channel flow
por: Su, Jinyu, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tscmlqf9ak6dkthf90jr152t9c