Blocking retrograde axonal transport of autophagosomes contributes to sevoflurane-induced neuron apoptosis in APP/PS1 mice

Autophagy, a crucial pathway for the degradation of proteins in eukaryotic cells, is linked to the development of Alzheimer’s disease (AD), and the accumulated autophagosomes in the cells resulting in the death of cells. Sevoflurane can impair spatial learning and memory in mice with AD and lead to...

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Detalles Bibliográficos
Autores principales: Xu, Mingliang, Feng, Jianguo, Tang, Mingxi, Guo, Qingxi, Zhan, Jian, Zhu, Fuzu, Lei, Hong, Kang, Qingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443487/
https://www.ncbi.nlm.nih.gov/pubmed/32385796
http://dx.doi.org/10.1007/s13760-020-01359-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443487/
https://www.ncbi.nlm.nih.gov/pubmed/32385796
http://dx.doi.org/10.1007/s13760-020-01359-6

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