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Blocking retrograde axonal transport of autophagosomes contributes to sevoflurane-induced neuron apoptosis in APP/PS1 mice
Autophagy, a crucial pathway for the degradation of proteins in eukaryotic cells, is linked to the development of Alzheimer’s disease (AD), and the accumulated autophagosomes in the cells resulting in the death of cells. Sevoflurane can impair spatial learning and memory in mice with AD and lead to...
Autores principales: | Xu, Mingliang, Feng, Jianguo, Tang, Mingxi, Guo, Qingxi, Zhan, Jian, Zhu, Fuzu, Lei, Hong, Kang, Qingmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443487/ https://www.ncbi.nlm.nih.gov/pubmed/32385796 http://dx.doi.org/10.1007/s13760-020-01359-6 |
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