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The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

The coronavirus disease 2019 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus, is a global health issue with unprecedented challenges for public health. SARS-CoV-2 primarily infects cells of the respiratory tract via spike glycoprotein binding to angiotens...

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Detalles Bibliográficos
Autores principales: Zhuang, Xiaodong, Tsukuda, Senko, Wrensch, Florian, Wing, Peter A.C., Schilling, Mirjam, Harris, James M., Borrmann, Helene, Morgan, Sophie B., Cane, Jennifer L., Mailly, Laurent, Thakur, Nazia, Conceicao, Carina, Sanghani, Harshmeena, Heydmann, Laura, Bach, Charlotte, Ashton, Anna, Walsh, Steven, Tan, Tiong Kit, Schimanski, Lisa, Huang, Kuan-Ying A., Schuster, Catherine, Watashi, Koichi, Hinks, Timothy S.C., Jagannath, Aarti, Vausdevan, Sridhar R., Bailey, Dalan, Baumert, Thomas F., McKeating, Jane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443536/
https://www.ncbi.nlm.nih.gov/pubmed/34545347
http://dx.doi.org/10.1016/j.isci.2021.103144