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Plateaus, rebounds and the effects of individual behaviours in epidemics

Plateaus and rebounds of various epidemiological indicators are widely reported in Covid-19 pandemics studies but have not been explained so far. Here, we address this problem and explain the appearance of these patterns. We start with an empirical study of an original dataset obtained from highly p...

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Autores principales: Berestycki, Henri, Desjardins, Benoît, Heintz, Bruno, Oury, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443568/
https://www.ncbi.nlm.nih.gov/pubmed/34526528
http://dx.doi.org/10.1038/s41598-021-97077-x
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author Berestycki, Henri
Desjardins, Benoît
Heintz, Bruno
Oury, Jean-Marc
author_facet Berestycki, Henri
Desjardins, Benoît
Heintz, Bruno
Oury, Jean-Marc
author_sort Berestycki, Henri
collection PubMed
description Plateaus and rebounds of various epidemiological indicators are widely reported in Covid-19 pandemics studies but have not been explained so far. Here, we address this problem and explain the appearance of these patterns. We start with an empirical study of an original dataset obtained from highly precise measurements of SARS-CoV-2 concentration in wastewater over nine months in several treatment plants around the Thau lagoon in France. Among various features, we observe that the concentration displays plateaus at different dates in various locations but at the same level. In order to understand these facts, we introduce a new mathematical model that takes into account the heterogeneity and the natural variability of individual behaviours. Our model shows that the distribution of risky behaviours appears as the key ingredient for understanding the observed temporal patterns of epidemics.
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spelling pubmed-84435682021-09-20 Plateaus, rebounds and the effects of individual behaviours in epidemics Berestycki, Henri Desjardins, Benoît Heintz, Bruno Oury, Jean-Marc Sci Rep Article Plateaus and rebounds of various epidemiological indicators are widely reported in Covid-19 pandemics studies but have not been explained so far. Here, we address this problem and explain the appearance of these patterns. We start with an empirical study of an original dataset obtained from highly precise measurements of SARS-CoV-2 concentration in wastewater over nine months in several treatment plants around the Thau lagoon in France. Among various features, we observe that the concentration displays plateaus at different dates in various locations but at the same level. In order to understand these facts, we introduce a new mathematical model that takes into account the heterogeneity and the natural variability of individual behaviours. Our model shows that the distribution of risky behaviours appears as the key ingredient for understanding the observed temporal patterns of epidemics. Nature Publishing Group UK 2021-09-15 /pmc/articles/PMC8443568/ /pubmed/34526528 http://dx.doi.org/10.1038/s41598-021-97077-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Berestycki, Henri
Desjardins, Benoît
Heintz, Bruno
Oury, Jean-Marc
Plateaus, rebounds and the effects of individual behaviours in epidemics
title Plateaus, rebounds and the effects of individual behaviours in epidemics
title_full Plateaus, rebounds and the effects of individual behaviours in epidemics
title_fullStr Plateaus, rebounds and the effects of individual behaviours in epidemics
title_full_unstemmed Plateaus, rebounds and the effects of individual behaviours in epidemics
title_short Plateaus, rebounds and the effects of individual behaviours in epidemics
title_sort plateaus, rebounds and the effects of individual behaviours in epidemics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443568/
https://www.ncbi.nlm.nih.gov/pubmed/34526528
http://dx.doi.org/10.1038/s41598-021-97077-x
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