Cargando…
Use of human PBMC to analyse the impact of obesity on lipid metabolism and metabolic status: a proof-of-concept pilot study
Peripheral blood mononuclear cells (PBMC) are widely used as a biomarker source in nutrition/obesity studies because they reflect gene expression profiles of internal tissues. In this pilot proof-of-concept study we analysed in humans if, as we previously suggested in rodents, PBMC could be a surrog...
Autores principales: | Costa, Andrea, Reynés, Bàrbara, Konieczna, Jadwiga, Martín, Marian, Fiol, Miquel, Palou, Andreu, Romaguera, Dora, Oliver, Paula |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443582/ https://www.ncbi.nlm.nih.gov/pubmed/34526523 http://dx.doi.org/10.1038/s41598-021-96981-6 |
Ejemplares similares
-
Impaired CPT1A Gene Expression Response to Retinoic Acid Treatment in Human PBMC as Predictor of Metabolic Risk
por: Cifre, Margalida, et al.
Publicado: (2020) -
Perinatal Treatment with Leptin, but Not Celastrol, Protects from Metabolically Obese, Normal-Weight Phenotype in Rats
por: Reynés, Bàrbara, et al.
Publicado: (2022) -
Blood cell transcriptomic-based early biomarkers of adverse programming effects of gestational calorie restriction and their reversibility by leptin supplementation
por: Konieczna, Jadwiga, et al.
Publicado: (2015) -
Whole Blood RNA as a Source of Transcript-Based Nutrition- and Metabolic Health-Related Biomarkers
por: Petrov, Petar D., et al.
Publicado: (2016) -
Oral Leptin Treatment in Suckling Rats Ameliorates Detrimental Effects in Hypothalamic Structure and Function Caused by Maternal Caloric Restriction during Gestation
por: Konieczna, Jadwiga, et al.
Publicado: (2013)