Hybrid derivative of cathelicidin and human beta defensin-2 against Gram-positive bacteria: A novel approach for the treatment of bacterial keratitis

Bacterial keratitis (BK) is a major cause of corneal blindness globally. This study aimed to develop a novel class of antimicrobial therapy, based on human-derived hybrid host defense peptides (HyHDPs), for treating BK. HyHDPs were rationally designed through combination of functional amino acids in...

Descripción completa

Detalles Bibliográficos
Autores principales: Ting, Darren Shu Jeng, Goh, Eunice Tze Leng, Mayandi, Venkatesh, Busoy, Joanna M. F., Aung, Thet Tun, Periayah, Mercy Halleluyah, Nubile, Mario, Mastropasqua, Leonardo, Said, Dalia G., Htoon, Hla M., Barathi, Veluchamy Amutha, Beuerman, Roger W., Lakshminarayanan, Rajamani, Mohammed, Imran, Dua, Harminder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443647/
https://www.ncbi.nlm.nih.gov/pubmed/34526600
http://dx.doi.org/10.1038/s41598-021-97821-3

Ejemplares similares

Ejemplares similares