Porphyromonas gingivalis induces entero-hepatic metabolic derangements with alteration of gut microbiota in a type 2 diabetes mouse model

Periodontal infection induces systemic inflammation; therefore, aggravating diabetes. Orally administered periodontal pathogens may directly alter the gut microbiota. We orally treated obese db/db diabetes mice using Porphyromonas gingivalis (Pg). We screened for Pg-specific peptides in the intestin...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Yoichiro, Aburaya, Shunsuke, Sugiyama, Naoyuki, Narukawa, Yuki, Sakamoto, Yuta, Takahashi, Masatomo, Uemura, Hayato, Yamashita, Rentaro, Tominaga, Shotaro, Hayashi, Satoko, Nozaki, Takenori, Yamada, Satoru, Izumi, Yoshihiro, Kashiwagi, Atsunori, Bamba, Takeshi, Ishihama, Yasushi, Murakami, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443650/
https://www.ncbi.nlm.nih.gov/pubmed/34526589
http://dx.doi.org/10.1038/s41598-021-97868-2

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