In situ identification and G4-PPI-His-Mal-dendrimer-induced reduction of early-stage amyloid aggregates in Alzheimer’s disease transgenic mice using synchrotron-based infrared imaging

Amyloid plaques composed of Aβ amyloid peptides and neurofibrillary tangles are a pathological hallmark of Alzheimer Disease. In situ identification of early-stage amyloid aggregates in Alzheimer’s disease is relevant for their importance as potential targets for effective drugs. Synchrotron-based i...

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Detalles Bibliográficos
Autores principales: Benseny-Cases, Núria, Álvarez-Marimon, Elena, Aso, Ester, Carmona, Margarita, Klementieva, Oxana, Appelhans, Dietmar, Ferrer, Isidre, Cladera, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443673/
https://www.ncbi.nlm.nih.gov/pubmed/34526539
http://dx.doi.org/10.1038/s41598-021-96379-4

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