Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily

Ligands of the transforming growth factor-β (TGF-β) superfamily are important targets for therapeutic intervention but present challenges because they signal combinatorially and exhibit overlapping activities in vivo. To obtain agents capable of sequestering multiple TGF-β superfamily ligands with n...

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Detalles Bibliográficos
Autores principales: Kumar, Ravindra, Grinberg, Asya V., Li, Huiming, Kuo, Tzu-Hsing, Sako, Dianne, Krishnan, Lavanya, Liharska, Katia, Li, Jia, Grenha, Rosa, Maguire, Michelle C., Briscoe, Steven D., Pearsall, R. Scott, Herrin, Brantley R., Suragani, Rajasekhar N. V. S., Castonguay, Roselyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443706/
https://www.ncbi.nlm.nih.gov/pubmed/34526551
http://dx.doi.org/10.1038/s41598-021-97203-9

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