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Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model
The development of new effective and safer therapies for osteoporosis, in addition to improved diagnostic and prevention strategies, represents a serious need in the scientific community. Micro-CT image-based analyses in association with biomechanical testing have become pivotal tools in identifying...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443718/ https://www.ncbi.nlm.nih.gov/pubmed/34526510 http://dx.doi.org/10.1038/s41597-021-01012-8 |
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author | Stephens, Maialen López-Linares, Karen Aldazabal, Javier Macias, Iratxe Ortuzar, Naiara Bengoetxea, Harkaitz Bulnes, Susana Alcorta-Sevillano, Natividad Infante, Arantza Lafuente, Jose Vicente Rodríguez, Clara I. |
author_facet | Stephens, Maialen López-Linares, Karen Aldazabal, Javier Macias, Iratxe Ortuzar, Naiara Bengoetxea, Harkaitz Bulnes, Susana Alcorta-Sevillano, Natividad Infante, Arantza Lafuente, Jose Vicente Rodríguez, Clara I. |
author_sort | Stephens, Maialen |
collection | PubMed |
description | The development of new effective and safer therapies for osteoporosis, in addition to improved diagnostic and prevention strategies, represents a serious need in the scientific community. Micro-CT image-based analyses in association with biomechanical testing have become pivotal tools in identifying osteoporosis in animal models by assessment of bone microarchitecture and resistance, as well as bone strength. Here, we describe a dataset of micro-CT scans and reconstructions of 15 whole femurs and biomechanical tests on contralateral femurs from C57BL/6JOlaHsd ovariectomized (OVX), resembling human post-menopausal osteoporosis, and sham operated (sham) female mice. Data provided for each mouse include: the acquisition images (.tiff), the reconstructed images (.bmp) and an.xls file containing the maximum attenuations for each reconstructed image. Biomechanical data include an.xls file with the recorded load-displacement, a movie with the filmed test and an.xls file collecting all biomechanical results. |
format | Online Article Text |
id | pubmed-8443718 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84437182021-10-04 Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model Stephens, Maialen López-Linares, Karen Aldazabal, Javier Macias, Iratxe Ortuzar, Naiara Bengoetxea, Harkaitz Bulnes, Susana Alcorta-Sevillano, Natividad Infante, Arantza Lafuente, Jose Vicente Rodríguez, Clara I. Sci Data Data Descriptor The development of new effective and safer therapies for osteoporosis, in addition to improved diagnostic and prevention strategies, represents a serious need in the scientific community. Micro-CT image-based analyses in association with biomechanical testing have become pivotal tools in identifying osteoporosis in animal models by assessment of bone microarchitecture and resistance, as well as bone strength. Here, we describe a dataset of micro-CT scans and reconstructions of 15 whole femurs and biomechanical tests on contralateral femurs from C57BL/6JOlaHsd ovariectomized (OVX), resembling human post-menopausal osteoporosis, and sham operated (sham) female mice. Data provided for each mouse include: the acquisition images (.tiff), the reconstructed images (.bmp) and an.xls file containing the maximum attenuations for each reconstructed image. Biomechanical data include an.xls file with the recorded load-displacement, a movie with the filmed test and an.xls file collecting all biomechanical results. Nature Publishing Group UK 2021-09-15 /pmc/articles/PMC8443718/ /pubmed/34526510 http://dx.doi.org/10.1038/s41597-021-01012-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) applies to the metadata files associated with this article. |
spellingShingle | Data Descriptor Stephens, Maialen López-Linares, Karen Aldazabal, Javier Macias, Iratxe Ortuzar, Naiara Bengoetxea, Harkaitz Bulnes, Susana Alcorta-Sevillano, Natividad Infante, Arantza Lafuente, Jose Vicente Rodríguez, Clara I. Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model |
title | Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model |
title_full | Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model |
title_fullStr | Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model |
title_full_unstemmed | Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model |
title_short | Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model |
title_sort | murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model |
topic | Data Descriptor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443718/ https://www.ncbi.nlm.nih.gov/pubmed/34526510 http://dx.doi.org/10.1038/s41597-021-01012-8 |
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