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Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
BACKGROUND: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443720/ https://www.ncbi.nlm.nih.gov/pubmed/34524577 http://dx.doi.org/10.1186/s12348-021-00263-1 |
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author | Testi, Ilaria Vermeirsch, Sandra Pavesio, Carlos |
author_facet | Testi, Ilaria Vermeirsch, Sandra Pavesio, Carlos |
author_sort | Testi, Ilaria |
collection | PubMed |
description | BACKGROUND: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better characterization of the morphology of this condition. METHODS: Narrative review. RESULTS: In this review, a comprehensive overview of clinical features, imaging findings, treatment management, and long-term outcomes of patients with APMPPE will be provided. CONCLUSIONS: Although APMPPE was originally believed to be a self-limited condition with a good prognosis, the disease can be recurrent and result in significant loss of vision function. Fundus imaging plays an important role in the diagnosis and management of the disease, allowing to evaluate response to treatment and onset of complications. |
format | Online Article Text |
id | pubmed-8443720 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-84437202021-10-08 Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) Testi, Ilaria Vermeirsch, Sandra Pavesio, Carlos J Ophthalmic Inflamm Infect Review BACKGROUND: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better characterization of the morphology of this condition. METHODS: Narrative review. RESULTS: In this review, a comprehensive overview of clinical features, imaging findings, treatment management, and long-term outcomes of patients with APMPPE will be provided. CONCLUSIONS: Although APMPPE was originally believed to be a self-limited condition with a good prognosis, the disease can be recurrent and result in significant loss of vision function. Fundus imaging plays an important role in the diagnosis and management of the disease, allowing to evaluate response to treatment and onset of complications. Springer Berlin Heidelberg 2021-09-16 /pmc/articles/PMC8443720/ /pubmed/34524577 http://dx.doi.org/10.1186/s12348-021-00263-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Testi, Ilaria Vermeirsch, Sandra Pavesio, Carlos Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) |
title | Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) |
title_full | Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) |
title_fullStr | Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) |
title_full_unstemmed | Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) |
title_short | Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) |
title_sort | acute posterior multifocal placoid pigment epitheliopathy (apmppe) |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443720/ https://www.ncbi.nlm.nih.gov/pubmed/34524577 http://dx.doi.org/10.1186/s12348-021-00263-1 |
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