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Lcz696 Alleviates Myocardial Fibrosis After Myocardial Infarction Through the sFRP-1/Wnt/β-Catenin Signaling Pathway

Background: Lcz696 (ARNI, angiotensin receptor–neprilysin inhibitor; sacubitril/valsartan) shows an inhibitory effect on fibrosis after myocardial infarction (MI). However, the underlying signaling mechanisms are poorly understood. The Wnt/β-catenin signaling pathway is activated after MI and partic...

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Detalles Bibliográficos
Autores principales:	Liu, Jing, Zheng, Xuehui, Zhang, Chen, Zhang, Chunmei, Bu, Peili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443774/ https://www.ncbi.nlm.nih.gov/pubmed/34539406 http://dx.doi.org/10.3389/fphar.2021.724147

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