Low Interleukin-22 Binding Protein Is Associated With High Mortality in Alcoholic Hepatitis and Modulates Interleukin-22 Receptor Expression

INTRODUCTION: In alcoholic hepatitis (AH), high interleukin (IL)-22 production is associated with disease improvement, purportedly through enhanced infection resistance and liver regeneration. IL-22 binding protein (BP) binds and antagonizes IL-22 bioactivity, but data on IL-22BP in liver disease su...

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Detalles Bibliográficos
Autores principales: Støy, Sidsel, Laursen, Tea Lund, Glavind, Emilie, Eriksen, Peter Lykke, Terczynska-Dyla, Ewa, Magnusson, Nils Erik, Hamilton-Dutoit, Stephen, Mortensen, Frank Viborg, Veidal, Sanne Skovgård, Rigbolt, Kristoffer, Riggio, Oliviero, Deleuran, Bent, Vilstrup, Hendrik, Sandahl, Thomas Damgaard.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443818/
https://www.ncbi.nlm.nih.gov/pubmed/32955203
http://dx.doi.org/10.14309/ctg.0000000000000197

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