Potential natural products that target the SARS-CoV-2 spike protein identified by structure-based virtual screening, isothermal titration calorimetry and lentivirus particles pseudotyped (Vpp) infection assay

BACKGROUND AND AIM: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters cells through the binding of the viral spike protein with human angiotensin-converting enzyme 2 (ACE2), resulting in the development of coronavirus disease 2019 (COVID-19). To date, few antiviral drugs are availa...

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Detalles Bibliográficos
Autores principales: Chen, Guan-Yu, Pan, Yi-Cheng, Wu, Tung-Ying, Yao, Tsung-You, Wang, Wei-Jan, Shen, Wan-Jou, Ahmed, Azaj, Chan, Shu-Ting, Tang, Chih-Hsin, Huang, Wei-Chien, Hung, Mien-Chie, Yang, Juan-Cheng, Wu, Yang-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443859/
https://www.ncbi.nlm.nih.gov/pubmed/34549024
http://dx.doi.org/10.1016/j.jtcme.2021.09.002

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