Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders

Psychiatric disorders are a collection of heterogeneous mental disorders arising from a contribution of genetic and environmental insults, many of which molecularly converge on transcriptional dysregulation, resulting in altered synaptic functions. The underlying mechanisms linking the genetic lesio...

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Detalles Bibliográficos
Autores principales: Wang, Xinyuan, Ye, Fei, Wen, Zhexing, Guo, Ziyuan, Yu, Chuan, Huang, Wei-Kai, Ringeling, Francisca Rojas, Su, Yijing, Zheng, Wei, Zhou, Guomin, Christian, Kimberly M., Song, Hongjun, Zhang, Mingjie, Ming, Guo-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444148/
https://www.ncbi.nlm.nih.gov/pubmed/31444471
http://dx.doi.org/10.1038/s41380-019-0485-2

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