Four-factor prothrombin complex concentrate to reduce allogenic blood product transfusion in patients with major trauma, the PROCOAG trial: study protocol for a randomized multicenter double-blind superiority study

BACKGROUND: Optimal management of severe trauma patients with active hemorrhage relies on adequate initial resuscitation. Early administration of coagulation factors improves post-traumatic coagulation disorders, and four-factor prothrombin complex concentrate (PCC) might be useful in this context....

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Detalles Bibliográficos
Autores principales: Bouzat, Pierre, Bosson, Jean-Luc, David, Jean-Stéphane, Riou, Bruno, Duranteau, Jacques, Payen, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444177/
https://www.ncbi.nlm.nih.gov/pubmed/34530886
http://dx.doi.org/10.1186/s13063-021-05524-x

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