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A CTLA-4 blocking strategy based on Nanoboby in dendritic cell-stimulated cytokine-induced killer cells enhances their anti-tumor effects

BACKGROUND: Cytokine-induced killer cells induced with tumor antigen-pulsed dendritic cells (DC-CIK) immunotherapy is a promising strategy for the treatment of malignant tumors. However, itsefficacy isrestricted by the immunosuppression, which is mediated by the cytotoxic T-lymphocyte-associated ant...

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Detalles Bibliográficos
Autores principales:	Wang, Wu, Wang, Xi, Yang, Wenli, Zhong, Kai, He, Na, Li, Xuexia, Pang, Yanyang, Lu, Zi, Liu, Aiqun, Lu, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444408/ https://www.ncbi.nlm.nih.gov/pubmed/34525966 http://dx.doi.org/10.1186/s12885-021-08732-5

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