Multi-centre, randomised non-inferiority trial of early treatment versus expectant management of patent ductus arteriosus in preterm infants (the BeNeDuctus trial): statistical analysis plan

BACKGROUND: Controversy exists about the optimal management of a patent ductus arteriosus (PDA) in preterm infants. A persistent PDA is associated with neonatal mortality and morbidity, but causality remains unproven. Although both pharmacological and/or surgical treatment are effective in PDA closu...

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Detalles Bibliográficos
Autores principales: Hundscheid, Tim, Donders, Rogier, Onland, Wes, Kooi, Elisabeth M. W., Vijlbrief, Daniel C., de Vries, Willem B., Nuytemans, Debbie H. G. M., van Overmeire, Bart, Mulder, Antonius L., de Boode, Willem P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Update
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444433/
https://www.ncbi.nlm.nih.gov/pubmed/34526095
http://dx.doi.org/10.1186/s13063-021-05594-x

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