Applications and challenges of CRISPR-Cas gene-editing to disease treatment in clinics

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems (Cas) are efficient tools for targeting specific genes for laboratory research, agricultural engineering, biotechnology, and human disease treatment. Cas9, by far the most extensively used gene-editing nuclease, ha...

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Detalles Bibliográficos
Autores principales: Liu, Wenyi, Li, Luoxi, Jiang, Jianxin, Wu, Min, Lin, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444435/
https://www.ncbi.nlm.nih.gov/pubmed/34541453
http://dx.doi.org/10.1093/pcmedi/pbab014