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The effect of genetically modified platelet-derived growth factor-BB over-expressing mesenchymal stromal cells during core decompression for steroid-associated osteonecrosis of the femoral head in rabbits

BACKGROUND: Approximately one third of patients undergoing core decompression (CD) for early-stage osteonecrosis of the femoral head (ONFH) experience progression of the disease, and subsequently require total hip arthroplasty (THA). Thus, identifying adjunctive treatments to optimize bone regenerat...

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Detalles Bibliográficos
Autores principales: Guzman, Roberto Alfonso, Maruyama, Masahiro, Moeinzadeh, Seyedsina, Lui, Elaine, Zhang, Ning, Storaci, Hunter W., Tam, Kaysie, Huang, Elijah Ejun, Utsunomiya, Takeshi, Rhee, Claire, Gao, Qi, Yao, Zhenyu, Yang, Yunzhi Peter, Goodman, Stuart B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444495/
https://www.ncbi.nlm.nih.gov/pubmed/34526115
http://dx.doi.org/10.1186/s13287-021-02572-7