Cargando…
MD2 contributes to the pathogenesis of perioperative neurocognitive disorder via the regulation of α5GABA(A) receptors in aged mice
BACKGROUND: Perioperative neurocognitive disorder (PND) is a long-term postoperative complication in elderly surgical patients. The underlying mechanism of PND is unclear, and no effective therapies are currently available. It is believed that neuroinflammation plays an important role in triggering...
Autores principales: | Zuo, Wenqiang, Zhao, Jianshuai, Zhang, Jinming, Fang, Zongping, Deng, Jiao, Fan, Ze, Guo, Yaru, Han, Jing, Hou, Wugang, Dong, Hailong, Xu, Feifei, Xiong, Lize |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444589/ https://www.ncbi.nlm.nih.gov/pubmed/34530841 http://dx.doi.org/10.1186/s12974-021-02246-4 |
Ejemplares similares
-
A decrease in NR2B expression mediated by DNA hypermethylation induces perioperative neurocognitive disorder in aged mice
por: Xu, Feifei, et al.
Publicado: (2023) -
Integration of ATAC-Seq and RNA-Seq identifies key genes and pathways involved in the neuroprotection of S-adenosylmethionine against perioperative neurocognitive disorder
por: Xu, Feifei, et al.
Publicado: (2023) -
Complement activation contributes to perioperative neurocognitive disorders in mice
por: Xiong, Chao, et al.
Publicado: (2018) -
Targeting neuroinflammation as a preventive and therapeutic approach for perioperative neurocognitive disorders
por: Cheng, Chun, et al.
Publicado: (2022) -
A modified mouse model of perioperative neurocognitive disorders exacerbated by sleep fragmentation
por: Wu, Tingmei, et al.
Publicado: (2022)