Cargando…

Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae

We present a case of a 34-year-old male with coronavirus disease 2019 (COVID-19) and uncontrolled blood sugar with right orbital cellulitis and right ethmoidal and maxillary sinusitis. Histopathology of a middle meatus tissue biopsy collected via diagnostic nasal endoscopy (DNE) revealed the presenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wadhwa, Lovish, Khurana, Shikhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445006/
https://www.ncbi.nlm.nih.gov/pubmed/34540475
http://dx.doi.org/10.7759/cureus.17249
_version_ 1784568567438508032
author Wadhwa, Lovish
Khurana, Shikhar
author_facet Wadhwa, Lovish
Khurana, Shikhar
author_sort Wadhwa, Lovish
collection PubMed
description We present a case of a 34-year-old male with coronavirus disease 2019 (COVID-19) and uncontrolled blood sugar with right orbital cellulitis and right ethmoidal and maxillary sinusitis. Histopathology of a middle meatus tissue biopsy collected via diagnostic nasal endoscopy (DNE) revealed the presence of Mucor and Klebsiella pneumoniae (K. pneumoniae). After the administration of intravenous (IV) insulin, cefoperazone-sulbactam, and posaconazole (due to the non-availability of amphotericin B), he underwent surgical debridement and functional endoscopic sinus surgery (FESS). After being on antibiotics and antifungals for two weeks post-surgery, the patient had a favorable outcome and further tests revealed improved blood counts and inflammatory markers.
format Online
Article
Text
id pubmed-8445006
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-84450062021-09-17 Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae Wadhwa, Lovish Khurana, Shikhar Cureus Endocrinology/Diabetes/Metabolism We present a case of a 34-year-old male with coronavirus disease 2019 (COVID-19) and uncontrolled blood sugar with right orbital cellulitis and right ethmoidal and maxillary sinusitis. Histopathology of a middle meatus tissue biopsy collected via diagnostic nasal endoscopy (DNE) revealed the presence of Mucor and Klebsiella pneumoniae (K. pneumoniae). After the administration of intravenous (IV) insulin, cefoperazone-sulbactam, and posaconazole (due to the non-availability of amphotericin B), he underwent surgical debridement and functional endoscopic sinus surgery (FESS). After being on antibiotics and antifungals for two weeks post-surgery, the patient had a favorable outcome and further tests revealed improved blood counts and inflammatory markers. Cureus 2021-08-17 /pmc/articles/PMC8445006/ /pubmed/34540475 http://dx.doi.org/10.7759/cureus.17249 Text en Copyright © 2021, Wadhwa et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Wadhwa, Lovish
Khurana, Shikhar
Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae
title Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae
title_full Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae
title_fullStr Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae
title_full_unstemmed Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae
title_short Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae
title_sort rhino-orbital mucormycosis in a covid-19 patient co-infected with klebsiella pneumoniae
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445006/
https://www.ncbi.nlm.nih.gov/pubmed/34540475
http://dx.doi.org/10.7759/cureus.17249
work_keys_str_mv AT wadhwalovish rhinoorbitalmucormycosisinacovid19patientcoinfectedwithklebsiellapneumoniae
AT khuranashikhar rhinoorbitalmucormycosisinacovid19patientcoinfectedwithklebsiellapneumoniae