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Minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - A single centre experience

CONTEXT: Emphysematous pyelonephritis (EPN) is a dangerous necrotizing infection of the kidney involving the diabetics with a high case fatality rate. Recent medical literature has shown shifting of treatment strategy from conventional radical approach to minimally invasive approach. AIMS: The aim o...

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Autores principales: Gite, VA, Shaw, V, Agrawal, M, Sankapal, P, Maheshwari, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445114/
https://www.ncbi.nlm.nih.gov/pubmed/34380801
http://dx.doi.org/10.4103/jpgm.JPGM_1315_20
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author Gite, VA
Shaw, V
Agrawal, M
Sankapal, P
Maheshwari, M
author_facet Gite, VA
Shaw, V
Agrawal, M
Sankapal, P
Maheshwari, M
author_sort Gite, VA
collection PubMed
description CONTEXT: Emphysematous pyelonephritis (EPN) is a dangerous necrotizing infection of the kidney involving the diabetics with a high case fatality rate. Recent medical literature has shown shifting of treatment strategy from conventional radical approach to minimally invasive approach. AIMS: The aim of our study was to assess the role of minimally invasive stepwise decompression techniques in the management of EPN and preservation of the renal unit. SETTINGS AND DESIGN: : This was a retrospective observational study conducted from June 2017 to April 2020 at a tertiary care centre. MATERIAL AND METHODS: We reviewed the hospital online records of 18 patients diagnosed with EPN for patient demographics, clinical profiles, co-morbidities, laboratory and, radiological investigations, surgical interventions performed and the outcomes. The severity of EPN was graded as per the Huang classification. Patients underwent surgical interventions as per the treatment protocol and response was assessed. STATISTICAL ANALYSIS USED: Descriptive statistics was applied. RESULTS: Diabetes mellitus was present in 15 (83.3%) patients along with urinary tract obstruction in 8 (44.4%) patients. Flank pain (77.7%) was the most common presenting clinical feature while Escherichia coli (55.5%) were the most common causative organism. Most patients (50%) had Type- II EPN, all of which were managed successfully by minimally invasive procedures. In total seventeen patients (94.4%) responded well while one patient (5.5%) underwent nephrectomy with no mortality. CONCLUSIONS: Renal salvage in EPN requires multidisciplinary approach including the initial medical management followed by properly selected stepwise decompressive surgical techniques. Conservative management and decompression techniques have shown to improve patient's outcome, reducing the traditional morbidity associated with nephrectomy.
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spelling pubmed-84451142021-09-27 Minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - A single centre experience Gite, VA Shaw, V Agrawal, M Sankapal, P Maheshwari, M J Postgrad Med Original Article CONTEXT: Emphysematous pyelonephritis (EPN) is a dangerous necrotizing infection of the kidney involving the diabetics with a high case fatality rate. Recent medical literature has shown shifting of treatment strategy from conventional radical approach to minimally invasive approach. AIMS: The aim of our study was to assess the role of minimally invasive stepwise decompression techniques in the management of EPN and preservation of the renal unit. SETTINGS AND DESIGN: : This was a retrospective observational study conducted from June 2017 to April 2020 at a tertiary care centre. MATERIAL AND METHODS: We reviewed the hospital online records of 18 patients diagnosed with EPN for patient demographics, clinical profiles, co-morbidities, laboratory and, radiological investigations, surgical interventions performed and the outcomes. The severity of EPN was graded as per the Huang classification. Patients underwent surgical interventions as per the treatment protocol and response was assessed. STATISTICAL ANALYSIS USED: Descriptive statistics was applied. RESULTS: Diabetes mellitus was present in 15 (83.3%) patients along with urinary tract obstruction in 8 (44.4%) patients. Flank pain (77.7%) was the most common presenting clinical feature while Escherichia coli (55.5%) were the most common causative organism. Most patients (50%) had Type- II EPN, all of which were managed successfully by minimally invasive procedures. In total seventeen patients (94.4%) responded well while one patient (5.5%) underwent nephrectomy with no mortality. CONCLUSIONS: Renal salvage in EPN requires multidisciplinary approach including the initial medical management followed by properly selected stepwise decompressive surgical techniques. Conservative management and decompression techniques have shown to improve patient's outcome, reducing the traditional morbidity associated with nephrectomy. Wolters Kluwer - Medknow 2021 2021-08-03 /pmc/articles/PMC8445114/ /pubmed/34380801 http://dx.doi.org/10.4103/jpgm.JPGM_1315_20 Text en Copyright: © 2021 Journal of Postgraduate Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Gite, VA
Shaw, V
Agrawal, M
Sankapal, P
Maheshwari, M
Minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - A single centre experience
title Minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - A single centre experience
title_full Minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - A single centre experience
title_fullStr Minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - A single centre experience
title_full_unstemmed Minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - A single centre experience
title_short Minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - A single centre experience
title_sort minimally invasive techniques as a first line approach in the management of emphysematous pyelonephritis - a single centre experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445114/
https://www.ncbi.nlm.nih.gov/pubmed/34380801
http://dx.doi.org/10.4103/jpgm.JPGM_1315_20
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