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Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis

Scleredema adultorum of Buschke is a rare disorder of the connective tissue, involving the skin. Here, we present a 61-year-old male, who is a known case of compensated liver cirrhosis with a past history of being treated for autoimmune thyrotoxicosis, who presented with complaints of alopecia, skin...

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Autores principales: Muralidharan, S, Arun, K, Ruckmani, V, Devi, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445121/
https://www.ncbi.nlm.nih.gov/pubmed/34380804
http://dx.doi.org/10.4103/jpgm.JPGM_1214_20
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author Muralidharan, S
Arun, K
Ruckmani, V
Devi, B
author_facet Muralidharan, S
Arun, K
Ruckmani, V
Devi, B
author_sort Muralidharan, S
collection PubMed
description Scleredema adultorum of Buschke is a rare disorder of the connective tissue, involving the skin. Here, we present a 61-year-old male, who is a known case of compensated liver cirrhosis with a past history of being treated for autoimmune thyrotoxicosis, who presented with complaints of alopecia, skin tightening, dry skin, pruritus, and woody indurated plaques on the skin of the upper back, shoulder, and arms. Skin biopsy of the arm revealed the characteristic features of scleredema. He was extensively evaluated for known literature-cited causes of scleredema, and the work up revealed a negative result. He was also found to be hypothyroid on presentation. Hence, we present a case of scleredema occurring in a patient with hypothyroidism and chronic liver disease, which to our knowledge is being described for the first time in literature.
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spelling pubmed-84451212021-09-27 Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis Muralidharan, S Arun, K Ruckmani, V Devi, B J Postgrad Med Case Report Scleredema adultorum of Buschke is a rare disorder of the connective tissue, involving the skin. Here, we present a 61-year-old male, who is a known case of compensated liver cirrhosis with a past history of being treated for autoimmune thyrotoxicosis, who presented with complaints of alopecia, skin tightening, dry skin, pruritus, and woody indurated plaques on the skin of the upper back, shoulder, and arms. Skin biopsy of the arm revealed the characteristic features of scleredema. He was extensively evaluated for known literature-cited causes of scleredema, and the work up revealed a negative result. He was also found to be hypothyroid on presentation. Hence, we present a case of scleredema occurring in a patient with hypothyroidism and chronic liver disease, which to our knowledge is being described for the first time in literature. Wolters Kluwer - Medknow 2021 2021-08-12 /pmc/articles/PMC8445121/ /pubmed/34380804 http://dx.doi.org/10.4103/jpgm.JPGM_1214_20 Text en Copyright: © 2021 Journal of Postgraduate Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Muralidharan, S
Arun, K
Ruckmani, V
Devi, B
Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis
title Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis
title_full Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis
title_fullStr Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis
title_full_unstemmed Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis
title_short Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis
title_sort scleredema adultorum of buschke associated with hypothyroidism and liver cirrhosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445121/
https://www.ncbi.nlm.nih.gov/pubmed/34380804
http://dx.doi.org/10.4103/jpgm.JPGM_1214_20
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