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Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis
Scleredema adultorum of Buschke is a rare disorder of the connective tissue, involving the skin. Here, we present a 61-year-old male, who is a known case of compensated liver cirrhosis with a past history of being treated for autoimmune thyrotoxicosis, who presented with complaints of alopecia, skin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445121/ https://www.ncbi.nlm.nih.gov/pubmed/34380804 http://dx.doi.org/10.4103/jpgm.JPGM_1214_20 |
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author | Muralidharan, S Arun, K Ruckmani, V Devi, B |
author_facet | Muralidharan, S Arun, K Ruckmani, V Devi, B |
author_sort | Muralidharan, S |
collection | PubMed |
description | Scleredema adultorum of Buschke is a rare disorder of the connective tissue, involving the skin. Here, we present a 61-year-old male, who is a known case of compensated liver cirrhosis with a past history of being treated for autoimmune thyrotoxicosis, who presented with complaints of alopecia, skin tightening, dry skin, pruritus, and woody indurated plaques on the skin of the upper back, shoulder, and arms. Skin biopsy of the arm revealed the characteristic features of scleredema. He was extensively evaluated for known literature-cited causes of scleredema, and the work up revealed a negative result. He was also found to be hypothyroid on presentation. Hence, we present a case of scleredema occurring in a patient with hypothyroidism and chronic liver disease, which to our knowledge is being described for the first time in literature. |
format | Online Article Text |
id | pubmed-8445121 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-84451212021-09-27 Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis Muralidharan, S Arun, K Ruckmani, V Devi, B J Postgrad Med Case Report Scleredema adultorum of Buschke is a rare disorder of the connective tissue, involving the skin. Here, we present a 61-year-old male, who is a known case of compensated liver cirrhosis with a past history of being treated for autoimmune thyrotoxicosis, who presented with complaints of alopecia, skin tightening, dry skin, pruritus, and woody indurated plaques on the skin of the upper back, shoulder, and arms. Skin biopsy of the arm revealed the characteristic features of scleredema. He was extensively evaluated for known literature-cited causes of scleredema, and the work up revealed a negative result. He was also found to be hypothyroid on presentation. Hence, we present a case of scleredema occurring in a patient with hypothyroidism and chronic liver disease, which to our knowledge is being described for the first time in literature. Wolters Kluwer - Medknow 2021 2021-08-12 /pmc/articles/PMC8445121/ /pubmed/34380804 http://dx.doi.org/10.4103/jpgm.JPGM_1214_20 Text en Copyright: © 2021 Journal of Postgraduate Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Muralidharan, S Arun, K Ruckmani, V Devi, B Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis |
title | Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis |
title_full | Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis |
title_fullStr | Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis |
title_full_unstemmed | Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis |
title_short | Scleredema adultorum of Buschke associated with hypothyroidism and liver cirrhosis |
title_sort | scleredema adultorum of buschke associated with hypothyroidism and liver cirrhosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445121/ https://www.ncbi.nlm.nih.gov/pubmed/34380804 http://dx.doi.org/10.4103/jpgm.JPGM_1214_20 |
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