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A Nonlethal Murine Flame Burn Model Leads to a Transient Reduction in Host Defenses and Enhanced Susceptibility to Lethal Pseudomonas aeruginosa Infection
Of the 486,000 burn injuries that required medical treatment in the United States in 2016, 40,000 people were hospitalized, with >3,000 fatalities. After burn injury, humans are at increased risk of sepsis and mortality from infections caused by Pseudomonas aeruginosa, an opportunistic pathogen....
Autores principales: | Brammer, Jerod, Choi, Myeongjin, Baliban, Scott M., Kambouris, Adrienne R., Fiskum, Gary, Chao, Wei, Lopez, Kerri, Miller, Catriona, Al-Abed, Yousef, Vogel, Stefanie N., Simon, Raphael, Cross, Alan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445176/ https://www.ncbi.nlm.nih.gov/pubmed/34152806 http://dx.doi.org/10.1128/IAI.00091-21 |
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