Evolutionary and functional lessons from human-specific amino acid substitution matrices

Human genetic variation in coding regions is fundamental to the study of protein structure and function. Most methods for interpreting missense variants consider substitution measures derived from homologous proteins across different species. In this study, we introduce human-specific amino acid (AA...

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Detalles Bibliográficos
Autores principales: Shauli, Tair, Brandes, Nadav, Linial, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445205/
https://www.ncbi.nlm.nih.gov/pubmed/34541526
http://dx.doi.org/10.1093/nargab/lqab079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445205/
https://www.ncbi.nlm.nih.gov/pubmed/34541526
http://dx.doi.org/10.1093/nargab/lqab079

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