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Relationship between hemagglutinin stability and influenza virus persistence after exposure to low pH or supraphysiological heating

The hemagglutinin (HA) surface glycoprotein is triggered by endosomal low pH to cause membrane fusion during influenza A virus (IAV) entry yet must remain sufficiently stable to avoid premature activation during virion transit between cells and hosts. HA activation pH and/or virion inactivation pH v...

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Detalles Bibliográficos
Autores principales: Yang, Guohua, Ojha, Chet R., Russell, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445419/
https://www.ncbi.nlm.nih.gov/pubmed/34478484
http://dx.doi.org/10.1371/journal.ppat.1009910

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