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Cracking it - successful mRNA extraction for digital gene expression analysis from decalcified, formalin-fixed and paraffin-embedded bone tissue

With the advance of precision medicine, the availability of tumor tissue for molecular analysis has become a limiting factor. This is particularly the case for bone metastases which are frequently occurring in cancer types such as prostate cancer. Due to the necessary decalcification process it was...

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Detalles Bibliográficos
Autores principales: Saraji, Alireza, Offermann, Anne, Stegmann-Frehse, Janine, Hempel, Katharina, Kang, Duan, Krupar, Rosemarie, Watermann, Christian, Jonigk, Danny, Kühnel, Mark Philipp, Kirfel, Jutta, Perner, Sven, Sailer, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445430/
https://www.ncbi.nlm.nih.gov/pubmed/34529723
http://dx.doi.org/10.1371/journal.pone.0257416