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On cross-ancestry cancer polygenic risk scores

Polygenic risk scores (PRS) can provide useful information for personalized risk stratification and disease risk assessment, especially when combined with non-genetic risk factors. However, their construction depends on the availability of summary statistics from genome-wide association studies (GWA...

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Detalles Bibliográficos
Autores principales: Fritsche, Lars G., Ma, Ying, Zhang, Daiwei, Salvatore, Maxwell, Lee, Seunggeun, Zhou, Xiang, Mukherjee, Bhramar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445431/
https://www.ncbi.nlm.nih.gov/pubmed/34529658
http://dx.doi.org/10.1371/journal.pgen.1009670

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