Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

Prior studies have demonstrated that immunologic dysfunction underpins severe illness in COVID-19 patients, but have lacked an in-depth analysis of the immunologic drivers of death in the most critically ill patients. We performed immunophenotyping of viral antigen-specific and unconventional T cell...

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Detalles Bibliográficos
Autores principales: Youngs, Jonathan, Provine, Nicholas M., Lim, Nicholas, Sharpe, Hannah R., Amini, Ali, Chen, Yi-Ling, Luo, Jian, Edmans, Matthew D., Zacharopoulou, Panagiota, Chen, Wentao, Sampson, Oliver, Paton, Robert, Hurt, William J., Duncan, David A., McNaughton, Anna L., Miao, Vincent N., Leaver, Susannah, Wyncoll, Duncan L. A., Ball, Jonathan, Hopkins, Philip, Skelly, Donal T., Barnes, Eleanor, Dunachie, Susanna, Ogg, Graham, Lambe, Teresa, Pavord, Ian, Shalek, Alex K., Thompson, Craig P., Xue, Luzheng, Macallan, Derek C., Goulder, Philip, Klenerman, Paul, Bicanic, Tihana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445447/
https://www.ncbi.nlm.nih.gov/pubmed/34529726
http://dx.doi.org/10.1371/journal.ppat.1009804

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