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Histone demethylase LSD1 promotes RIG-I poly-ubiquitination and anti-viral gene expression

Under RNA virus infection, retinoic acid-inducible gene I (RIG-I) in host cells recognizes viral RNA and activates the expression of type I IFN. To investigate the roles of protein methyltransferases and demethylases in RIG-I antiviral signaling pathway, we screened all the known related enzymes wit...

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Detalles Bibliográficos
Autores principales:	Hu, Qi-Xin, Wang, Hui-Yi, Jiang, Lu, Wang, Chen-Yu, Ju, Lin-Gao, Zhu, Yuan, Zhong, Bo, Wu, Min, Wang, Zhen, Li, Lian-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445485/ https://www.ncbi.nlm.nih.gov/pubmed/34529741 http://dx.doi.org/10.1371/journal.ppat.1009918

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