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Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor

Rho GTPases are regulatory proteins, which orchestrate cell features such as morphology, polarity and movement. Therefore, probing Rho GTPase activity is key to understanding processes such as development and cell migration. Localization-based reporters for active Rho GTPases are attractive probes t...

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Detalles Bibliográficos
Autores principales: Mahlandt, Eike K., Arts, Janine J. G., van der Meer, Werner J., van der Linden, Franka H., Tol, Simon, van Buul, Jaap D., Gadella, Theodorus W. J., Goedhart, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445605/
https://www.ncbi.nlm.nih.gov/pubmed/34357388
http://dx.doi.org/10.1242/jcs.258823

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