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Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor
Rho GTPases are regulatory proteins, which orchestrate cell features such as morphology, polarity and movement. Therefore, probing Rho GTPase activity is key to understanding processes such as development and cell migration. Localization-based reporters for active Rho GTPases are attractive probes t...
Autores principales: | Mahlandt, Eike K., Arts, Janine J. G., van der Meer, Werner J., van der Linden, Franka H., Tol, Simon, van Buul, Jaap D., Gadella, Theodorus W. J., Goedhart, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445605/ https://www.ncbi.nlm.nih.gov/pubmed/34357388 http://dx.doi.org/10.1242/jcs.258823 |
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