Mesenchymal stromal cell aging impairs the self-organizing capacity of lung alveolar epithelial stem cells

Multicellular organisms maintain structure and function of tissues/organs through emergent, self-organizing behavior. In this report, we demonstrate a critical role for lung mesenchymal stromal cell (L-MSC) aging in determining the capacity to form three-dimensional organoids or ‘alveolospheres’ wit...

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Detalles Bibliográficos
Autores principales: Chanda, Diptiman, Rehan, Mohammad, Smith, Samuel R, Dsouza, Kevin G, Wang, Yong, Bernard, Karen, Kurundkar, Deepali, Memula, Vinayak, Kojima, Kyoko, Mobley, James A, Benavides, Gloria A, Darley-Usmar, Victor, Kim, Young-iL, Zmijewski, Jaroslaw W, Deshane, Jessy S, De Langhe, Stijn, Thannickal, Victor J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445616/
https://www.ncbi.nlm.nih.gov/pubmed/34528872
http://dx.doi.org/10.7554/eLife.68049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445616/
https://www.ncbi.nlm.nih.gov/pubmed/34528872
http://dx.doi.org/10.7554/eLife.68049

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