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Anti-influenza A Virus Effects and Mechanisms of Emodin and Its Analogs via Regulating PPARα/γ-AMPK-SIRT1 Pathway and Fatty Acid Metabolism

The peroxisome proliferator-activated receptor (PPAR) α/γ-adenosine 5′-monophosphate- (AMP-) activated protein kinase- (AMPK-) sirtuin-1 (SIRT1) pathway and fatty acid metabolism are reported to be involved in influenza A virus (IAV) replication and IAV-pneumonia. Through a cell-based peroxisome pro...

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Detalles Bibliográficos
Autores principales: Bei, Yufei, Tia, Boyu, Li, Yuze, Guo, Yingzhu, Deng, Shufei, Huang, Rouyu, Zeng, Huiling, Li, Rui, Wang, Ge-Fei, Dai, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445710/
https://www.ncbi.nlm.nih.gov/pubmed/34540999
http://dx.doi.org/10.1155/2021/9066938

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