E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion

The ubiquitin-proteasome system maintains protein homoeostasis, underpins the cell cycle, and is dysregulated in cancer. However, the role of individual E3 ubiquitin ligases, which mediate the final step in ubiquitin-mediated proteolysis, remains incompletely understood. Identified through screening...

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Detalles Bibliográficos
Autores principales: Ottina, Eleonora, Panova, Veera, Doglio, Laura, Kazachenka, Anastasiya, Cornish, Georgina, Kirkpatrick, Joanna, Attig, Jan, Young, George R., Litchfield, Kevin, Lesluyes, Tom, Van Loo, Peter, Swanton, Charles, MacRae, James, Tüting, Thomas, Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445817/
https://www.ncbi.nlm.nih.gov/pubmed/34145398
http://dx.doi.org/10.1038/s41388-021-01885-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445817/
https://www.ncbi.nlm.nih.gov/pubmed/34145398
http://dx.doi.org/10.1038/s41388-021-01885-4

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