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E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion
The ubiquitin-proteasome system maintains protein homoeostasis, underpins the cell cycle, and is dysregulated in cancer. However, the role of individual E3 ubiquitin ligases, which mediate the final step in ubiquitin-mediated proteolysis, remains incompletely understood. Identified through screening...
Autores principales: | Ottina, Eleonora, Panova, Veera, Doglio, Laura, Kazachenka, Anastasiya, Cornish, Georgina, Kirkpatrick, Joanna, Attig, Jan, Young, George R., Litchfield, Kevin, Lesluyes, Tom, Van Loo, Peter, Swanton, Charles, MacRae, James, Tüting, Thomas, Kassiotis, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445817/ https://www.ncbi.nlm.nih.gov/pubmed/34145398 http://dx.doi.org/10.1038/s41388-021-01885-4 |
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