Cargando…

Positive feedback regulation of lncRNA PVT1 and HIF2α contributes to clear cell renal cell carcinoma tumorigenesis and metastasis

Long noncoding RNAs (lncRNAs) have been reported to exert important roles in tumors, including clear cell renal cell carcinoma (ccRCC). PVT1 is an important oncogenic lncRNA which has critical effects on onset and development of various cancers, however, the underlying mechanism of PVT1 functioning...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ming-xiao, Zhang, Li-zhen, Fu, Liang-min, Yao, Hao-hua, Tan, Lei, Feng, Zi-hao, Li, Jia-ying, Lu, Jun, Pan, Yi-hui, Shu, Guan-nan, Li, Peng-ju, Tang, Yi-ming, Liao, Zhuang-yao, Wei, Jin-huan, Chen, Wei, Guo, Jian-ping, Luo, Jun-hang, Chen, Zhen-hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445819/ https://www.ncbi.nlm.nih.gov/pubmed/34321604 http://dx.doi.org/10.1038/s41388-021-01971-7

Ejemplares similares

Noncoding RNA PVT1 in osteosarcoma: The roles of lncRNA PVT1 and circPVT1
por: Wu, Tingrui, et al.
Publicado: (2022)

lncRNA PVT1 and its splicing variant function as competing endogenous RNA to regulate clear cell renal cell carcinoma progression
por: Yang, Tao, et al.
Publicado: (2017)

A positive feedback regulatory loop involving the lncRNA PVT1 and HIF-1α in pancreatic cancer
por: Zhu, Yiping, et al.
Publicado: (2021)

Role of LncRNA score and PVT1 in primary hyperparathyroidism-- a preliminary study
por: Zhang, Dongxue, et al.
Publicado: (2021)

LncRNA PVT1 promotes malignant progression in squamous cell carcinoma of the head and neck
por: Yu, Changyun, et al.
Publicado: (2018)

Downregulation of lncRNA PVT1 expression inhibits proliferation and migration by regulating p38 expression in prostate cancer
por: Wan, Bo, et al.
Publicado: (2018)

Positive Reciprocal Feedback of lncRNA ZEB1-AS1 and HIF-1α Contributes to Hypoxia-Promoted Tumorigenesis and Metastasis of Pancreatic Cancer
por: Jin, Yan, et al.
Publicado: (2021)

LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24
por: Lv, Tao, et al.
Publicado: (2021)

UPF1 Participates in the Progression of Endometrial Cancer by Inhibiting the Expression of lncRNA PVT1
por: Xing, Tian-rong, et al.
Publicado: (2020)

Exosomal lncRNA PVT1/VEGFA Axis Promotes Colon Cancer Metastasis and Stemness by Downregulation of Tumor Suppressor miR-152-3p
por: Lai, Shiue-Wei, et al.
Publicado: (2021)

lncRNA PVT1: a novel oncogene in multiple cancers
por: Li, Ruiming, et al.
Publicado: (2022)

Corrigendum: Positive Reciprocal Feedback of LncRNA ZEB1-AS1 and HIF-1α Contributes to Hypoxia–Promoted Tumorigenesis and Metastasis of Pancreatic Cancer
por: Jin, Yan, et al.
Publicado: (2021)

The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1α
por: Wang, Ying, et al.
Publicado: (2019)

lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis
por: Wu, Hailu, et al.
Publicado: (2020)

The prognostic value of miRNA-18a-5p in clear cell renal cell carcinoma and its function via the miRNA-18a-5p/HIF1A/PVT1 pathway
por: Wang, Huan, et al.
Publicado: (2020)

LncRNA ADAMTS9-AS2 inhibits cell proliferation and decreases chemoresistance in clear cell renal cell carcinoma via the miR-27a-3p/FOXO1 axis
por: Song, Er-lin, et al.
Publicado: (2019)

Circulating exosomal lncRNA contributes to the pathogenesis of spinal cord injury in rats
por: Li, Jian-An, et al.
Publicado: (2022)

Knockdown of lncRNA PVT1 Inhibits Glioma Progression by Regulating miR-424 Expression
por: Han, Yanjie, et al.
Publicado: (2019)

Role and Mechanism of lncRNA-pvt1 in the Pathogenesis of Acute Lymphoblastic Leukemia in Children
por: Cheng, Yanli, et al.
Publicado: (2022)

LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma
por: Li, Yuan, et al.
Publicado: (2020)

lncRNA PVT1 in the Pathogenesis and Clinical Management of Renal Cell Carcinoma
por: Bohosova, Julia, et al.
Publicado: (2021)

Prognostic Value of lncRNA PVT1 for Patients with Gastric Cancer: A Meta-Analysis
por: Hao, Jinyong, et al.
Publicado: (2021)

Association of lncRNA PVT1 Gene Polymorphisms with the Risk of Essential Hypertension in Chinese Population
por: Li, Rong, et al.
Publicado: (2022)

Novel lncRNA UPLA1 mediates tumorigenesis and prognosis in lung adenocarcinoma
por: Han, Xiaoyang, et al.
Publicado: (2020)

Expression level and clinical significance of LncRNA PVT1 in the serum of patients with LEASO
por: Su, Xiaoxue, et al.
Publicado: (2023)

Long non-coding RNA PVT1 (PVT1) affects the expression of CCND1 and promotes doxorubicin resistance in osteosarcoma cells
por: Li, Zi, et al.
Publicado: (2023)

Construction of a pancreatic cancer prediction model for oxidative stress-related lncRNA
por: Huang, Hao, et al.
Publicado: (2023)

LncRNA PVT1 as an effective biomarker for cancer diagnosis and detection based on transcriptome data and meta-analysis
por: Zeng, Yunhong, et al.
Publicado: (2017)

Chemotherapeutic Risk lncRNA-PVT1 SNP Sensitizes Metastatic Colorectal Cancer to FOLFOX Regimen
por: Wu, Shenshen, et al.
Publicado: (2022)

LncRNA PVT1 Enhances Proliferation and Cisplatin Resistance via Regulating miR-194-5p/HIF1a Axis in Oral Squamous Cell Carcinoma
por: Wang, Fang, et al.
Publicado: (2020)

m6A-immune-related lncRNA prognostic signature for predicting immune landscape and prognosis of bladder cancer
por: Feng, Zi-Hao, et al.
Publicado: (2022)

Upregulated lncRNA Pvt1 may be important for cardiac remodeling at the infarct border zone
por: Liu, Baihui, et al.
Publicado: (2020)

LncRNA PWAR6 regulates proliferation and migration by epigenetically silencing YAP1 in tumorigenesis of pancreatic ductal adenocarcinoma
por: Huang, Shanshan, et al.
Publicado: (2021)

The lncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis
por: Iden, Marissa, et al.
Publicado: (2016)

A Novel Tumor Mutation Burden Related lncRNA Signature Identified Prognosis and Tumor Immune Microenvironment Features in Clear Cell Renal Cell Carcinoma
por: Lin, Lin, et al.
Publicado: (2023)

LncRNA PVT1 Promotes Cell Proliferation, Invasion, and Migration and Inhibits Cell Apoptosis by Phosphorylating YAP
por: Ji, Kaiyue, et al.
Publicado: (2022)

LncRNA PVT1 promotes ovarian cancer progression by silencing miR-214
por: Chen, Ying, et al.
Publicado: (2018)

Regulation of lncRNA PVT1 on miR-125 in metastasis of gastric cancer cells
por: Niu, Jiatai, et al.
Publicado: (2020)

LncRNA PVT1 is increased in renal cell carcinoma and affects viability and migration in vitro
por: Bohosova, Julia, et al.
Publicado: (2022)

LncRNA TUG1 contributes to the tumorigenesis of lung adenocarcinoma by regulating miR-138-5p-HIF1A axis
por: Li, Ke, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mj03vtsnkj4oleogdrd0529p2r