Cargando…

Ghrelin protects against lipopolysaccharide-induced acute respiratory distress syndrome through the PI3K/AKT pathway

Pulmonary endothelial barrier dysfunction is a major pathophysiology observed in acute respiratory distress syndrome (ARDS). Ghrelin, a key regulator of metabolism, has been shown to play protective roles in the respiratory system. However, its effects on lipopolysaccharide (LPS)-induced pulmonary e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lishan, Ge, Shanhui, He, Wanmei, Chen, Qingui, Xu, Caixia, Zeng, Mian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445891/ https://www.ncbi.nlm.nih.gov/pubmed/34437900 http://dx.doi.org/10.1016/j.jbc.2021.101111

Ejemplares similares

Overexpression of HOXB4 Promotes Protection of Bone Marrow Mesenchymal Stem Cells Against Lipopolysaccharide-Induced Acute Lung Injury Partially Through the Activation of Wnt/β-Catenin Signaling
por: Lin, Shan, et al.
Publicado: (2021)

Overexpression of FoxM1 optimizes the therapeutic effect of bone marrow mesenchymal stem cells on acute respiratory distress syndrome
por: Luo, Yuling, et al.
Publicado: (2023)

Prognosis predictive value of the Oxford Acute Severity of Illness Score for sepsis: a retrospective cohort study
por: Chen, Qingui, et al.
Publicado: (2019)

Association of Cardiac Troponin T Concentration on Admission with Prognosis in Critically Ill Patients without Myocardial Infarction: A Cohort Study
por: Xie, Ruijie, et al.
Publicado: (2021)

Association between Body Mass Index and Short-Term Clinical Outcomes in Critically Ill Patients with Sepsis: A Real-World Study
por: Lin, Shan, et al.
Publicado: (2020)

Association between comorbid diabetes mellitus and prognosis of patients with sepsis in the intensive care unit: a retrospective cohort study
por: Lin, Shan, et al.
Publicado: (2021)

Effects of ghrelin on the apoptosis of human neutrophils in vitro
por: Li, Bin, et al.
Publicado: (2016)

The Association of Red Blood Cell Distribution Width to Platelet Count Ratio and 28-Day Mortality of Patients with Sepsis: A Retrospective Cohort Study
por: Ge, Shanhui, et al.
Publicado: (2020)

Predictive value of ADAMTS-13 on concealed chronic renal failure in COPD patients
por: Zeng, Mian, et al.
Publicado: (2017)

Penehyclidine hydrochloride protects against lipopolysaccharide-induced acute lung injury by promoting the PI3K/Akt pathway
por: Weng, Junting, et al.
Publicado: (2023)

D-tagatose protects against oleic acid-induced acute respiratory distress syndrome in rats by activating PTEN/PI3K/AKT pathway
por: Huang, Jian, et al.
Publicado: (2022)

Cardiomyocyte protective effects of thyroid hormone during hypoxia/reoxygenation injury through activating of IGF‐1‐mediated PI3K/Akt signalling
por: Zeng, Bin, et al.
Publicado: (2021)

Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway
por: Zhao, Yuan, et al.
Publicado: (2020)

Overexpression of FoxM1 Enhanced the Protective Effect of Bone Marrow-Derived Mesenchymal Stem Cells on Lipopolysaccharide-Induced Acute Lung Injury through the Activation of Wnt/β-Catenin Signaling
por: Luo, Yuling, et al.
Publicado: (2023)

Modulation of telomere protection by the PI3K/AKT pathway
por: Méndez-Pertuz, Marinela, et al.
Publicado: (2017)

Daidzein Protects Caco-2 Cells against Lipopolysaccharide-Induced Intestinal Epithelial Barrier Injury by Suppressing PI3K/AKT and P38 Pathways
por: Zhang, Baoping, et al.
Publicado: (2022)

Adiponectin Attenuates Lipopolysaccharide-induced Apoptosis by Regulating the Cx43/PI3K/AKT Pathway
por: Liu, Luqian, et al.
Publicado: (2021)

S-allylmercaptocysteine inhibits mucin overexpression and inflammation via MAPKs and PI3K-Akt signaling pathways in acute respiratory distress syndrome
por: An, Lulu, et al.
Publicado: (2020)

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT
por: Baldanzi, Gianluca, et al.
Publicado: (2002)

Up-regulation of miR-146b-3p protects septic mice with acute respiratory distress syndrome by inhibiting PI3K/AKT signaling pathway
por: Liu, Yao, et al.
Publicado: (2020)

Capsaicin Protects Against Lipopolysaccharide-Induced Acute Lung Injury Through the HMGB1/NF-κB and PI3K/AKT/mTOR Pathways
por: Chen, Hui, et al.
Publicado: (2021)

Achyranthes bidentata polypeptide alleviates neurotoxicity of lipopolysaccharide-activated microglia via PI3K/Akt dependent NOX2/ROS pathway
por: Wang, Yitong, et al.
Publicado: (2021)

Protective effects of HY1702 on lipopolysaccharide-induced mild acute respiratory distress syndrome in mice
por: Wang, Mengfei, et al.
Publicado: (2020)

Benazepril hydrochloride protects against doxorubicin cardiotoxicity by regulating the PI3K/Akt pathway
por: Zhan, Lan, et al.
Publicado: (2021)

Neferine Protects Endothelial Glycocalyx via Mitochondrial ROS in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome
por: Liu, Xiang-Yong, et al.
Publicado: (2018)

Ghrelin and vascular protection
por: Pearson, James T, et al.
Publicado: (2019)

Ghrelin Improves Functional Survival of Engrafted Adipose-Derived Mesenchymal Stem Cells in Ischemic Heart through PI3K/Akt Signaling Pathway
por: Han, Dong, et al.
Publicado: (2015)

Ghrelin inhibits cisplatin-induced MDA-MB-231 breast cancer cell apoptosis via PI3K/Akt/mTOR signaling
por: Zhang, Jinyu, et al.
Publicado: (2020)

Low Dose of Lipopolysaccharide Pretreatment Preventing Subsequent Endotoxin-Induced Uveitis Is Associated with PI3K/AKT Pathway
por: Zhang, Nan, et al.
Publicado: (2017)

Eupafolin ameliorates lipopolysaccharide-induced cardiomyocyte autophagy via PI3K/AKT/mTOR signaling pathway
por: Gao, Yan, et al.
Publicado: (2019)

Crocin alleviates lipopolysaccharide-induced acute respiratory distress syndrome by protecting against glycocalyx damage and suppressing inflammatory signaling pathways
por: Zhang, Dong, et al.
Publicado: (2020)

Control of the PI3K/Akt pathway by porcine reproductive and respiratory syndrome virus
por: Zhu, Liqian, et al.
Publicado: (2013)

Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway
por: El-kott, Attalla Farag, et al.
Publicado: (2019)

Ligustrazine ameliorates lipopolysaccharide-induced neurocognitive impairment by activating autophagy via the PI3K/AKT/mTOR pathway
por: Li, Guangming, et al.
Publicado: (2020)

Involvement of ghrelin in the neonatal exposure to lipopolysaccharide and thermoregulation during endotoxemia in adulthood
por: Ferrari, Mayara Andrade, et al.
Publicado: (2013)

Comprehensive Analysis of Potential ceRNA Network and Different Degrees of Immune Cell Infiltration in Acute Respiratory Distress Syndrome
por: Hu, Jiaxin, et al.
Publicado: (2022)

Ghrelin Protects against the Detrimental Consequences of Porphyromonas gingivalis-Induced Akt Inactivation through S-Nitrosylation on Salivary Mucin Synthesis
por: Slomiany, Bronislaw L., et al.
Publicado: (2011)

Dhcr24 activates the PI3K/Akt/HKII pathway and protects against dilated cardiomyopathy in mice
por: Dong, Wei, et al.
Publicado: (2018)

Piperine protects against myocardial ischemia/reperfusion injury by activating the PI3K/AKT signaling pathway
por: Li, Yun-Peng, et al.
Publicado: (2021)

The protective role of human ghrelin in sepsis: Restoration of CD4 T cell proliferation
por: Zhou, Mian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_daricvmjv38amkd8qgjkv12a2m