Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance

BACKGROUND & AIMS: Chronic inflammation in colon section is associated with an increased risk of colorectal cancer (CRC). Proinflammatory cytokines were produced in a tumor microenvironment and correlated with poor clinical outcome. Tumor-infiltrating T cells were reported to be greatly involved...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Liu, Xiuting, Zhou, Wei, Du, Qianming, Yang, Mengdi, Ding, Yang, Hu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445903/
https://www.ncbi.nlm.nih.gov/pubmed/34087454
http://dx.doi.org/10.1016/j.jcmgh.2021.05.018

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