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Targeting integrin αvβ3 by a rationally designed protein for chronic liver disease treatment
Chronic Liver Diseases (CLD) are characterized by abnormal accumulation of collagen fibrils, neo-angiogenesis, and sinusoidal remodeling. Collagen deposition along with intrahepatic angiogenesis and sinusoidal remodeling alters sinusoid structure resulting in portal hypertension, liver failure, and...
Autores principales: | Turaga, Ravi Chakra, Satyanarayana, Ganesh, Sharma, Malvika, Yang, Jenny J., Wang, Shiyuan, Liu, Chunfeng, Li, Sun, Yang, Hua, Grossniklaus, Hans, Farris, Alton Brad, Gracia-Sancho, Jordi, Liu, Zhi-Ren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445973/ https://www.ncbi.nlm.nih.gov/pubmed/34531529 http://dx.doi.org/10.1038/s42003-021-02611-2 |
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