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Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N‐formyl peptide receptors agonists

N‐formyl peptide receptors (FPR1, FPR2, and FPR3) play key roles in the regulation of inflammatory processes, and recently, it was demonstrated that FPR1 and FPR2 have a dual role in the progression/suppression of some cancers. Therefore, FPRs represent an important therapeutic target for the treatm...

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Detalles Bibliográficos
Autores principales: Vergelli, Claudia, Khlebnikov, Andrei I., Crocetti, Letizia, Guerrini, Gabriella, Cantini, Niccolò, Kirpotina, Liliya N., Schepetkin, Igor A., Cilibrizzi, Agostino, Quinn, Mark T., Rossi, Patrizia, Paoli, Paola, Giovannoni, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446315/
https://www.ncbi.nlm.nih.gov/pubmed/34148303
http://dx.doi.org/10.1111/cbdd.13913